CCNE1 and survival of patients with tubo‐ovarian high‐grade serous carcinoma: An Ovarian Tumor Tissue Analysis consortium study

Author:

Kang Eun‐Young1,Weir Ashley234,Meagher Nicola S.25ORCID,Farrington Kyo1,Nelson Gregg S.6,Ghatage Prafull6,Lee Cheng‐Han7ORCID,Riggan Marjorie J.8,Bolithon Adelyn39,Popovic Gordana10,Leung Betty11,Tang Katrina12,Lambie Neil13,Millstein Joshua14,Alsop Jennifer15,Anglesio Michael S.1617,Ataseven Beyhan1819,Barlow Ellen20,Beckmann Matthias W.21,Berger Jessica22,Bisinotto Christiani23,Bösmüller Hans24,Boros Jessica252627,Brand Alison H.2627,Brooks‐Wilson Angela28,Brucker Sara Y.29,Carney Michael E.30,Casablanca Yovanni31,Cazorla‐Jiménez Alicia32,Cohen Paul A.3334,Conrads Thomas P.35,Cook Linda S.3637,Coulson Penny38,Courtney‐Brooks Madeleine22,Cramer Daniel W.3940,Crowe Philip1141,Cunningham Julie M.42,Cybulski Cezary43,Darcy Kathleen M.4445,El‐Bahrawy Mona A.46,Elishaev Esther47,Erber Ramona48,Farrell Rhonda49,Fereday Sian5051ORCID,Fischer Anna24,García María J.52,Gayther Simon A.53,Gentry‐Maharaj Aleksandra54,Gilks C. Blake55,Grube Marcel29,Harnett Paul R.2756,Harrington Shariska Petersen57,Harter Philipp1858,Hartmann Arndt48,Hecht Jonathan L.59,Heikaus Sebastian60,Hein Alexander21,Heitz Florian185860,Hendley Joy50,Hernandez Brenda Y.61,Polo Susanna Hernando62,Heublein Sabine63,Hirasawa Akira64,Høgdall Estrid65,Høgdall Claus K.66,Horlings Hugo M.67,Huntsman David G.1668,Huzarski Tomasz4369,Jewell Andrea57,Jimenez‐Linan Mercedes70,Jones Michael E.38,Kaufmann Scott H.71,Kennedy Catherine J.252627ORCID,Khabele Dineo72,Kommoss Felix K. F.73,Kruitwagen Roy F. P. M.7475,Lambrechts Diether7677,Le Nhu D.78,Lener Marcin79,Lester Jenny80,Leung Yee818283,Linder Anna84,Loverix Liselore85,Lubiński Jan43,Madan Rashna86,Maxwell G. Larry87,Modugno Francesmary228889,Neuhausen Susan L.90,Olawaiye Alexander22,Olbrecht Siel85,Orsulic Sandra80,Palacios José91,Pearce Celeste Leigh92,Pike Malcolm C.9394,Quinn Carmel M.95,Mohan Ganendra Raj3382,Rodríguez‐Antona Cristina9697,Ruebner Matthias21,Ryan Andy5498,Salfinger Stuart G.33,Sasamoto Naoko39ORCID,Schildkraut Joellen M.99ORCID,Schoemaker Minouk J.38,Shah Mitul15,Sharma Raghwa100,Shvetsov Yurii B.61,Singh Naveena101,Sonke Gabe S.102,Steele Linda90,Stewart Colin J. R.103,Sundfeldt Karin84,Swerdlow Anthony J.38104,Talhouk Aline1617ORCID,Tan Adeline81105,Taylor Sarah E.22,Terry Kathryn L.3940,Tołoczko Aleksandra106,Traficante Nadia5051,Van de Vijver Koen K.107108,van der Aa Maaike A.109,Van Gorp Toon85,Van Nieuwenhuysen Els85,van‐Wagensveld Lilian7475109,Vergote Ignace85ORCID,Vierkant Robert A.110,Wang Chen111,Wilkens Lynne R.61,Winham Stacey J.111,Wu Anna H.94,Benitez Javier97112,Berchuck Andrew8,Candido dos Reis Francisco J.23,DeFazio Anna5252627,Fasching Peter A.21,Goode Ellen L.113,Goodman Marc T.114,Gronwald Jacek43,Karlan Beth Y.80,Kommoss Stefan29,Menon Usha54,Sinn Hans‐Peter73,Staebler Annette24,Brenton James D.115,Bowtell David D.5051,Pharoah Paul D. P.15116,Ramus Susan J.23,Köbel Martin1ORCID,

Affiliation:

1. Department of Pathology and Laboratory Medicine University of Calgary Foothills Medical Center Calgary Alberta Canada

2. School of Clinical Medicine UNSW Medicine and Health University of NSW Sydney Sydney New South Wales Australia

3. Adult Cancer Program Lowy Cancer Research Centre University of NSW Sydney Sydney New South Wales Australia

4. The Walter and Eliza Hall Institute of Medical Research Parkville Victoria Australia

5. The Daffodil Centre The University of Sydney A Joint Venture With Cancer Council NSW Sydney New South Wales Australia

6. Department of Oncology Division of Gynecologic Oncology Cumming School of Medicine University of Calgary Calgary Alberta Canada

7. Department of Pathology and Laboratory Medicine University of Alberta Edmonton Alberta Canada

8. Department of Obstetrics and Gynecology Division of Gynecologic Oncology Duke University Medical Center Durham North Carolina USA

9. School of Women's and Children's Health Faculty of Medicine and Health University of NSW Sydney Sydney New South Wales Australia

10. Stats Central Mark Wainwright Analytical Centre University of NSW Sydney Sydney New South Wales Australia

11. Prince of Wales Clinical School UNSW Medicine and Health University of NSW Sydney Sydney New South Wales Australia

12. Department of Anatomical Pathology Prince of Wales Hospital Sydney New South Wales Australia

13. Canterbury Health Laboratories Christchurch New Zealand

14. Division of Biostatistics Department of Population and Public Health Sciences Keck School of Medicine University of Southern California Los Angeles California USA

15. Department of Oncology Centre for Cancer Genetic Epidemiology University of Cambridge Cambridge UK

16. Department of Obstetrics and Gynecology University of British Columbia Vancouver British Columbia Canada

17. British Columbia's Gynecological Cancer Research Team (OVCARE) University of British Columbia BC Cancer and Vancouver General Hospital Vancouver British Columbia Canada

18. Department of Gynecology and Gynecologic Oncology Evangelische Kliniken Essen‐Mitte (KEM) Essen Germany

19. Department of Obstetrics and Gynecology Ludwig Maximilian University Munich Munich Germany

20. Gynaecological Cancer Centre Royal Hospital for Women Sydney New South Wales Australia

21. Department of Gynecology and Obstetrics Comprehensive Cancer Center Erlangen‐EMN Friedrich‐Alexander University Erlangen‐Nuremberg University Hospital Erlangen Erlangen Germany

22. Division of Gynecologic Oncology Department of Obstetrics, Gynecology and Reproductive Sciences University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA

23. Department of Gynecology and Obstetrics Ribeirão Preto Medical School University of São Paulo Ribeirão Preto Brazil

24. Institute of Pathology and Neuropathology Tuebingen University Hospital Tuebingen Germany

25. Centre for Cancer Research The Westmead Institute for Medical Research University of Sydney Sydney New South Wales Australia

26. Department of Gynaecological Oncology Westmead Hospital Sydney New South Wales Australia

27. Discipline of Obstetrics and Gynaecology The University of Sydney Sydney New South Wales Australia

28. Canada's Michael Smith Genome Sciences Centre BC Cancer Vancouver British Columbia Canada

29. Department of Women's Health Tuebingen University Hospital Tuebingen Germany

30. Department of Obstetrics and Gynecology John A. Burns School of Medicine University of Hawaii Honolulu Hawaii USA

31. Uniformed Services of the Health Sciences Gynecologic Cancer Center of Excellence Bethesda Maryland USA

32. Pathology Department Fundación Jiménez Díaz Madrid Spain

33. Department of Gynaecological Oncology St John of God Subiaco Hospital Subiaco Western Australia Australia

34. Division of Obstetrics and Gynaecology Medical School University of Western Australia Crawley Western Australia Australia

35. Women's Health Integrated Research Center Inova Health System Falls Church Virginia USA

36. Epidemiology School of Public Health University of Colorado Aurora Colorado USA

37. Community Health Sciences University of Calgary Calgary Alberta Canada

38. Division of Genetics and Epidemiology The Institute of Cancer Research London UK

39. Obstetrics and Gynecology Epidemiology Center Department of Obstetrics and Gynecology Brigham and Women's Hospital and Harvard Medical School Boston Massachusetts USA

40. Department of Epidemiology Harvard T.H. Chan School of Public Health Boston Massachusetts USA

41. Department of Surgery Prince of Wales Private Hospital Randwick New South Wales Australia

42. Department of Laboratory Medicine and Pathology Mayo Clinic Rochester Minnesota USA

43. Department of Genetics and Pathology International Hereditary Cancer Center Pomeranian Medical University Szczecin Poland

44. Gynecologic Cancer Center of Excellence Department of Gynecologic Surgery and Obstetrics Uniformed Services University of the Health Sciences Walter Reed National Military Medical Center Bethesda Maryland USA

45. Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc Bethesda Maryland USA

46. Department of Metabolism, Digestion and Reproduction Imperial College London Hammersmith Hospital London UK

47. Department of Pathology University of Pittsburgh School of Medicine Pittsburgh Pennsylvania USA

48. Institute of Pathology Comprehensive Cancer Center Erlangen‐EMN Friedrich‐Alexander University Erlangen‐Nuremberg University Hospital Erlangen Erlangen Germany

49. Prince of Wales Private Hospital Randwick New South Wales Australia

50. Peter MacCallum Cancer Centre Melbourne Victoria Australia

51. Sir Peter MacCallum Department of Oncology The University of Melbourne Parkville Victoria Australia

52. Computational Oncology Group Structural Biology Programme Spanish National Cancer Research Centre (CNIO) Madrid Spain

53. Center for Bioinformatics and Functional Genomics and the Cedars Sinai Genomics Core Cedars‐Sinai Medical Center Los Angeles California USA

54. MRC Clinical Trials Unit Institute of Clinical Trials & Methodology University College London London UK

55. Department of Pathology and Laboratory Medicine University of British Columbia Vancouver British Columbia Canada

56. Crown Princess Mary Cancer Centre Westmead Hospital Sydney New South Wales Australia

57. Division of Gynecologic Oncology Department of Obstetrics and Gynecology The University of Kansas Medical Center Kansas City Kansas USA

58. Department of Gynecology and Gynecological Oncology HSK, Dr. Horst‐Schmidt Klinik Wiesbaden Wiesbaden Germany

59. Department of Pathology Beth Israel Deaconess Medical Center and Harvard Medical School Boston Massachusetts USA

60. Center for Pathology Evangelische Kliniken Essen‐Mitte Essen Germany

61. University of Hawaii Cancer Center Honolulu Hawaii USA

62. Medical Oncology Service Hospital Universitario Funcación Alcorcón Alcorcón Spain

63. Department of Obstetrics and Gynecology University Hospital Heidelberg Heidelberg Germany

64. Department of Clinical Genomic Medicine Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Okayama University Okayama Japan

65. Department of Pathology Herlev Hospital University of Copenhagen Copenhagen Denmark

66. Department of Gynaecology Rigshospitalet University of Copenhagen Copenhagen Denmark

67. Division of Molecular Pathology The Netherlands Cancer Institute Amsterdam The Netherlands

68. Department of Molecular Oncology BC Cancer Research Centre Vancouver British Columbia Canada

69. Department of Genetics and Pathology University of Zielona Gora Zielona Gora Poland

70. Department of Histopathology Addenbrooke's Hospital Cambridge UK

71. Division of Oncology Research and Department of Molecular Pharmacology & Experimental Therapeutics Mayo Clinic Rochester Minnesota USA

72. Division of Gynecologic Oncology Department of Obstetrics and Gynecology Washington University in St. Louis St. Louis Missouri USA

73. Institute of Pathology Heidelberg University Hospital Heidelberg Germany

74. Department of Obstetrics and Gynecology Maastricht University Medical Centre Maastricht The Netherlands

75. GROW – School for Oncology and Reproduction Maastricht University Medical Center Maastricht The Netherlands

76. Department of Human Genetics Laboratory for Translational Genetics KU Leuven Leuven Belgium

77. VIB Center for Cancer Biology VIB Leuven Belgium

78. Cancer Control Research BC Cancer Agency Vancouver British Columbia Canada

79. International Hereditary Cancer Center Department of Genetics and Pathology Pomeranian Medical University in Szczecin Szczecin Poland

80. David Geffen School of Medicine Department of Obstetrics and Gynecology University of California at Los Angeles Los Angeles California USA

81. Division of Obstetrics and Gynaecology Faculty of Health and Medical Sciences University of Western Australia Crawley Western Australia Australia

82. Department of Gynaecological Oncology King Edward Memorial Hospital Subiaco Western Australia Australia

83. Australia New Zealand Gynaecological Oncology Group Camperdown Australia

84. Department of Obstetrics and Gynecology Inst of Clinical Science, Sahlgrenska Center for Cancer Research University of Gothenburg Gothenburg Sweden

85. Division of Gynecologic Oncology Department of Gynecology and Obstetrics Leuven Cancer Institute Leuven Belgium

86. Department of Pathology and Laboratory Medicine The University of Kansas Medical Center Kansas City Kansas USA

87. Inova Health System Women's Service Line Falls Church Virginia USA

88. Department of Epidemiology University of Pittsburgh School of Public Health Pittsburgh Pennsylvania USA

89. Women's Cancer Research Center Magee‐Womens Research Institute and Hillman Cancer Center Pittsburgh Pennsylvania USA

90. Department of Population Sciences Beckman Research Institute of City of Hope Duarte California USA

91. Department of Pathology Hospital Ramón y Cajal Instituto Ramon y Cajal de Investigación Sanitaria (IRyCIS) CIBERONC Universidad de Alcalá Madrid Spain

92. Department of Epidemiology University of Michigan School of Public Health Ann Arbor Michigan USA

93. Department of Epidemiology and Biostatistics Memorial Sloan‐Kettering Cancer Center New York New York USA

94. Department of Population Health and Public Health Sciences Keck School of Medicine University of Southern California Norris Comprehensive Cancer Center Los Angeles California USA

95. The Health Precincts Biobank UNSW Biospecimen Services Mark Wainwright Analytical Centre University of NSW Sydney Sydney New South Wales Australia

96. Hereditary Endocrine Cancer Group Spanish National Cancer Research Center (CNIO) Madrid Spain

97. Centre for Biomedical Network Research on Rare Diseases (CIBERER) Instituto de Salud Carlos III Madrid Spain

98. Women's Cancer Institute for Women's Health University College London London UK

99. Department of Epidemiology Rollins School of Public Health Emory University Atlanta Georgia USA

100. Tissue Pathology and Diagnostic Oncology Westmead Hospital Sydney New South Wales Australia

101. Department of Pathology Barts Health National Health Service Trust London UK

102. Department of Medical Oncology The Netherlands Cancer Institute ‐ Antoni van Leeuwenhoek Hospital Amsterdam The Netherlands

103. School for Women's and Infants' Health University of Western Australia Perth Australia

104. Division of Breast Cancer Research The Institute of Cancer Research London UK

105. Gynaepath WA Clinipath (Sonic Healthcare) Osbourne Park Australia

106. Department of Genetics and Pathology Pomeranian Medical University Szczecin Poland

107. Department of Pathology Ghent University Hospital Cancer Research Institute Ghent (CRIG) Ghent Belgium

108. Department of Pathology Antwerp University Hospital Antwerp Belgium

109. Department of Research Netherlands Comprehensive Cancer Organization (IKNL) Utrecht The Netherlands

110. Department of Quantitative Health Sciences Division of Clinical Trials and Biostatistics Mayo Clinic Rochester Minnesota USA

111. Department of Quantitative Health Sciences Division of Computational Biology Mayo Clinic Rochester Minnesota USA

112. Human Genetics Group Spanish National Cancer Research Centre (CNIO) Madrid Spain

113. Department of Quantitative Health Sciences Division of Epidemiology Mayo Clinic Rochester Minnesota USA

114. Cancer Prevention and Control Program Cedars‐Sinai Cancer Cedars‐Sinai Medical Center Los Angeles California USA

115. Cancer Research UK Cambridge Institute University of Cambridge Cambridge UK

116. Department of Public Health and Primary Care Centre for Cancer Genetic Epidemiology University of Cambridge Cambridge UK

Funder

National Cancer Institute

Alberta Precision Laboratories

Publisher

Wiley

Subject

Cancer Research,Oncology

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