Deep learning‐based image analysis reveals significant differences in the number and distribution of mucosal CD3 and γδ T cells between Crohn's disease and ulcerative colitis

Author:

Røyset Elin Synnøve123ORCID,Sahlin Pettersen Henrik P12ORCID,Xu Weili4ORCID,Larbi Anis4ORCID,Sandvik Arne K156ORCID,Steigen Sonja E78ORCID,Catalan‐Serra Ignacio169ORCID,Bakke Ingunn13ORCID

Affiliation:

1. Department of Clinical and Molecular Medicine (IKOM), Faculty of Medicine and Health Sciences (MH) NTNU – Norwegian University of Science and Technology Trondheim Norway

2. Department of Pathology, St. Olav's Hospital Trondheim University Hospital Trondheim Norway

3. Clinic of Laboratory Medicine, St. Olav's Hospital Trondheim University Hospital Trondheim Norway

4. Singapore Immunology Network (SIgN) Agency for Science Technology and Research, Biopolis Singapore

5. Department of Gastroenterology and Hepatology, Clinic of Medicine, St. Olav's Hospital Trondheim University Hospital Trondheim Norway

6. Centre of Molecular Inflammation Research (CEMIR) NTNU Trondheim Norway

7. Department of Medical Biology, Faculty of Health Sciences UiT The Arctic University of Norway Tromsø Norway

8. Department of Clinical Pathology University Hospital of North Norway Tromsø Norway

9. Department of Medicine, Gastroenterology Levanger Hospital, Nord‐Trøndelag Hospital Trust Levanger Norway

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Reference51 articles.

1. The burden of inflammatory bowel disease in Europe

2. Immunotherapy in inflammatory bowel disease: novel and emerging treatments;Catalan‐Serra I;Hum Vaccin Immunother,2018

3. Histologic scoring indices for evaluation of disease activity in ulcerative colitis;Mosli MH;Cochrane Database Syst Rev,2017

4. Histologic scoring indices for evaluation of disease activity in Crohn's disease;Novak G;Cochrane Database Syst Rev,2017

5. Maximizing the diagnostic information from biopsies in chronic inflammatory bowel diseases: recommendations from the Erlangen International Consensus Conference on Inflammatory Bowel Diseases and presentation of the IBD-DCA score as a proposal for a new index for histologic activity assessment in ulcerative colitis and Crohn’s disease

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