Inflammation‐dependent downregulation of miR‐194‐5p contributes to human intervertebral disc degeneration by targeting CUL4A and CUL4B

Author:

Chen Zhi1ORCID,Han Yingchao1,Deng Chao1,Chen Wei1,Jin Linyu1,Chen Hao1,Wang Kun1,Shen Hongxing1,Qian Lie1

Affiliation:

1. Department of Spine Surgery Renji Hospital, School of Medicine, Shanghai Jiao Tong University Shanghai China

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Cell Biology,Clinical Biochemistry,Physiology

Reference46 articles.

1. Intervertebral disc degeneration: biological biomechanical factors

2. Inhibition of miR‐27a suppresses the inflammatory response via the p38/MAPK pathway in intervertebral disc cells;Cao Z.;Experimental and Therapeutic Medicine,2017

3. Pro-inflammatory cytokines induce the transcription factors C/EBP? and C/EBP? in astrocytes

4. The human homologue for the Caenorhabditis elegans cul‐4 gene is amplified and overexpressed in primary breast cancers;Chen L. C.;Cancer Research,1998

5. Cullin Family Proteins and Tumorigenesis: Genetic Association and Molecular Mechanisms

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