Conformational fluctuations of the AXH monomer of Ataxin-1-Reference-Cited by-同舟云学术

Conformational fluctuations of the AXH monomer of Ataxin-1

Published:2015-11-23 Issue:1 Volume:84 Page:52-59
ISSN:0887-3585
Container-title:Proteins: Structure, Function, and Bioinformatics
language:en
Short-container-title:Proteins

Author:

Grasso Gianvito¹,Deriu Marco A.¹,Tuszynski Jack A.²,Gallo Diego³,Morbiducci Umberto³,Danani Andrea¹

Affiliation:

1. Istituto Dalle Molle Di Studi Sull'intelligenza Artificiale (IDSIA), Scuola Universitaria Professionale Della Svizzera Italiana (SUPSI), Università Della Svizzera Italiana (USI), Centro Galleria 2; Manno 6928 Switzerland

2. Department of Physics; University of Alberta; Edmonton, Alberta Canada

3. Department of Mechanical and Aerospace Engineering; Politecnico Di Torino; Corso Duca Degli Abruzzi 24 Torino 10128 Italy

Publisher

Wiley

Subject

Molecular Biology,Biochemistry,Structural Biology

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/prot.24954/fullpdf

Reference40 articles.

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2. Pathogenic mechanisms of a polyglutamine-mediated neurodegenerative disease, Spinocerebellar ataxia type 1;Zoghbi;J Biol Chem,2009

3. Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice;Emamian;Neuron,2003

4. Ataxin-1 nuclear localization and aggregation: role in polyglutarnine-induced disease in SCA1 transgenic mice;Klement;Cell,1998

5. Polyglutamine is not all: the functional role of the AXH domain in the ataxin-1 protein;Chiara;J Mol Biol,2005

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