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Assessment of Drug Transporter Function Using Fluorescent Cell Imaging

Published:2013-08 Issue:1 Volume:57 Page:
ISSN:1934-9254
Container-title:Current Protocols in Toxicology
language:en
Short-container-title:Current Protocols in Toxicology

Author:

Bircsak Kristin M.¹,Gibson Christopher J.¹,Robey Robert W.²,Aleksunes Lauren M.¹³

Affiliation:

1. Department of Pharmacology and Toxicology, Ernest Mario School of Pharmacy, Rutgers University Piscataway New Jersey

2. Medical Oncology Branch, National Cancer Institute, National Institutes of Health Bethesda Maryland

3. Environmental and Occupational Health Sciences Institute Piscataway New Jersey

Publisher

Wiley

Subject

Toxicology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/0471140856.tx2306s57

Reference36 articles.

1. Inhibition of P-glycoprotein transport function and reversion of MDR1 multidrug resistance by cnidiadin

2. Reversal of resistance by GF120918 in cell lines expressing the ABC half-transporter, MXR

3. P-Glycoprotein and Breast Cancer Resistance Protein: Two Dominant Transporters Working Together in Limiting the Brain Penetration of Topotecan

4. Evaluation and comparison of MRP1 activity with three fluorescent dyes and three modulators in leukemic cell lines

5. Comparison of ATP-Binding Cassette Transporter Interactions with the Tyrosine Kinase Inhibitors Imatinib, Nilotinib, and Dasatinib

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1. Method for Testing of Drugs Belonging to Substrates and Inhibitors of the Transporter Protein BCRP on Caco-2 Cells;Drug development & registration;2023-05-28

2. Fluorescence-based methods for studying activity and drug-drug interactions of hepatic solute carrier and ATP binding cassette proteins involved in ADME-Tox;Biochemical Pharmacology;2023-03

3. Establishment of ion channel and ABC transporter assays in 3D-cultured ReNcell VM on a 384-pillar plate for neurotoxicity potential;Toxicology in Vitro;2022-08

4. Healthy and diseased placenta barrier on-a-chip models suitable for high-throughput studies;2022-07-02

5. Low oxygen tension differentially regulates the expression of placental solute carriers and ABC transporters;FEBS Letters;2020-10-07

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