Pre‐Plated Cell Lines for ADMETox Applications in the Pharmaceutical Industry
Author:
Affiliation:
1. ReadyCell S. L., Barcelona, Spain
2. shared first authorship
3. Solvo Biotechnology, Budaörs, Hungary
4. Bioinvitro Division, Leitat Technological Center, Terrassa, Spain
5. shared senior authorship
Publisher
Wiley
Subject
Toxicology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/0471140856.tx2308s65
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1. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
2. Determination of Chinese hamster ovary cell line stability and recombinant antibody expression during long-term culture
3. Functional dissociation of paracellular permeability and transepithelial electrical resistance and disruption of the apical-basolateral intramembrane diffusion barrier by expression of a mutant tight junction membrane protein.
4. A tunable Caco-2/HT29-MTX co-culture model mimicking variable permeabilities of the human intestine obtained by an original seeding procedure
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