New syngeneic inflammatory-related lung cancer metastatic model harboring double KRAS/WWOX alterations

Author:

Bleau Anne-Marie1,Freire Javier12,Pajares María José12,Zudaire Isabel1,Anton Iker1,Nistal-Villán Estanislao3,Redrado Miriam1,Zandueta Caroli na1,Garmendia Irati12,Ajona Daniel1,Blanco David1,Pio Ruben14,Lecanda Fernando1,Calvo Alfonso12,Montuenga Luis M.12

Affiliation:

1. Division of Oncology; Center for Applied Medical Research (CIMA); University of Navarra; Pamplona Spain

2. Department of Histology and Pathology; School of Medicine; University of Navarra; Pamplona Spain

3. Division of Hepatology and Gene Therapy; CIMA, University of Navarra; Pamplona Spain

4. Department of Biochemistry; School of Medicine; University of Navarra; Pamplona Spain

Funder

EU 7th Framework FP72007-2013

Narie Curie Grant

RTICC

Spanish Minstry of Economy and Competitiveness

UTE-CIMA

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference46 articles.

1. Cancer statistics, 2009. CA;Jemal;Cancer J Clin,2009

2. SnapShot: non-small cell lung cancer;Heist;Cancer Cell,2012

3. Mouse models for human lung cancer;Meuwissen;Genes Dev,2005

4. Silica-induced chronic inflammation promotes lung carcinogenesis in the context of an immunosuppressive microenvironment;Freire;Neoplasia,2013

5. WWOX, a novel WW domain-containing protein mapping to human chromosome 16q23.3-24.1, a region frequently affected in breast cancer;Bednarek;Cancer Res,2000

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