Cetyl Myristoleate Isolated from Swiss Albino Mice: An Apparent Protective Agent against Adjuvant Arthritis in Rats

Author:

Diehl Harry W.,May Everette L.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference11 articles.

1. Mycoplasmal Arthritis of the Mouse: Development of Cellular Hypersensitivity to Normal Synovial Tissue

2. A sample of spermaceti oil from the case in the head of the sperm whale was provided by Dr. G. R. Peppit, Cancer Research Institute, Arizona State University, Tempe, AZ) and was examined by GC and direct-probe, chemical-ionization MS and found to contain 14% cetyl myristoleate or an isomer [identification by retention time and M+l (451) intensity only]. It should be noted that cis- 5-tetradecenoic acid, physteric acid, has been reported in a sperm whale head oil hydrolyzate. At the present time we have not ruled out a cetyl ester of this acid in our sample of spermaceti oil.

3. The Swiss albino mice were raised by the National Institutes of Health Animal Laboratory and had been used in the testing of analgesic compounds before being sacrificed.

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