Alkylation of 6-Mercaptopurine (6-MP) with N-Alkyl-N-alkoxycarbonyl)aminomethyl Chlorides: S6-(N-Alkyl-N-alkoxycarbonyl)aminomethyl-6-MP Prodrug Structure Effect on the Dermal Delivery of 6-MP-Reference-Cited by-同舟云学术

Alkylation of 6-Mercaptopurine (6-MP) with N-Alkyl-N-alkoxycarbonyl)aminomethyl Chlorides: S6-(N-Alkyl-N-alkoxycarbonyl)aminomethyl-6-MP Prodrug Structure Effect on the Dermal Delivery of 6-MP

Published:1990-01 Issue:1 Volume:79 Page:66-73
ISSN:0022-3549
Container-title:Journal of Pharmaceutical Sciences
language:en
Short-container-title:Journal of Pharmaceutical Sciences

Author:

Siver Kevin G.,Sloan Kenneth B.

Publisher

Elsevier BV

Subject

Pharmaceutical Science

Reference30 articles.

1. In Design of Prodrugs;Bundgaard,1985

2. Synthesis and antihypertensive activity of some ester progenitors of methyldopa

3. A novel peptide delivery system involving peptidase activated prodrugs as antimicrobial agents. Synthesis and biological activity of peptidyl derivatives of 5-fluorouracil

4. A convenient synthesis of (acyloxy)alkyl .alpha.-ethers of phenols

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