Use of Unbound Drug Concentration in Blood to Discriminate Between Two Models of Hepatic Drug Elimination
Author:
Publisher
Elsevier BV
Subject
Pharmaceutical Science
Reference9 articles.
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1. Reassessing models of hepatic extraction;Journal of Biological Physics;2003
2. Modeling of drug elimination by the liver. 1. Main concepts and physiologically justified clearance models (a review);Pharmaceutical Chemistry Journal;1996-05
3. Axial tissue diffusion can account for the disparity between current models of hepatic elimination for lipophilic drugs;Journal of Pharmacokinetics and Biopharmaceutics;1992-02
4. Physiologic Models of Hepatic Drug Elimination;New Trends in Pharmacokinetics;1991
5. Evaluation of Protein Binding Effect on Local Disposition of Oxacillin in Rat Liver by a Two-compartment Dispersion Model;Journal of Pharmacy and Pharmacology;1990-09
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