Troxerutin regulates HIF ‐1α by activating JAK2 / STAT3 signaling to inhibit oxidative stress, inflammation, and apoptosis of cardiomyocytes induced by H 2 O 2-Reference-Cited by-同舟云学术

Troxerutin regulates HIF ‐1α by activating JAK2 / STAT3 signaling to inhibit oxidative stress, inflammation, and apoptosis of cardiomyocytes induced by H 2 O 2

Published:2021-10-07 Issue: Volume: Page:
ISSN:0272-4391
Container-title:Drug Development Research
language:en
Short-container-title:Drug Dev Res

Author:

Li Hui¹,Yang Min²,Lou Danfei³^ORCID

Affiliation:

1. Department of Cardiology Shanxi Chinese Medical Hospital Taiyuan Shanxi China

2. Department of Medical Oncology The Second Affiliate Hospital of Zhe Jiang Chinese Medical University Hangzhou Zhejiang China

3. Department of Geriatrics, Shanghai Municipal Hospital of Traditional Chinese Medicine Shanghai University of Traditional Chinese Medicine Shanghai China

Publisher

Wiley

Subject

Drug Discovery

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ddr.21885

Reference46 articles.

1. Oxygen‐independent regulation of HIF‐1: Novel involvement of PI3K/AKT/mTOR pathway in cancer;Agani F.;Current Cancer Drug Targets,2013

2. Troxerutin preconditioning and ischemic Postconditioning modulate inflammatory response after myocardial ischemia/reperfusion injury in rat model;Badalzadeh R.;Inflammation,2017

3. Downregulation of signal transduction and STAT3 expression exacerbates oxidative stress mediated by NLRP3 inflammasome;Bai H.;Neural Regeneration Research,2018

4. Radical trapping and lipid peroxidation during myocardial reperfusion injury–radical scavenging by troxerutin in comparison to mannitol;Blasig I. E.;Biomedica Biochimica Acta,1987

5. Molecular responses to hypoxia‐inducible factor 1α and beyond;Brocato J.;Molecular Pharmacology,2014

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