Overview of Transporters in Pharmacokinetics and Drug Discovery
Author:
Affiliation:
1. Drug Metabolism Pharmacokinetics & Clinical Pharmacology, Incyte Corporation; Wilmington Delaware
Publisher
Wiley
Subject
General Medicine
Link
http://onlinelibrary.wiley.com/wol1/doi/10.1002/cpph.46/fullpdf
Reference55 articles.
1. A prospective analysis of co-processed non-ionic surfactants in enhancing permeability of a model hydrophilic drug;Alvi;AAPS PharmSciTech,2014
2. Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites;Backman;Clinical Pharmacology and Therapeutics,2005
3. Roles of UGT, P450, and Gut Microbiota in the metabolism of epacadostat in humans;Boer;Drug Metabolism and Disposition,2016
4. The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): Implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients;Breedveld;Cancer Research,2005
5. In vitro methods to support transporter evaluation in drug discovery and development;Brouwer;Clinical Pharmacology & Therapeutics,2013
Cited by 10 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Prenatal opioid exposure significantly impacts placental protein kinase C (PKC) and drug transporters, leading to drug resistance and neonatal opioid withdrawal syndrome;Frontiers in Neuroscience;2024-08-19
2. Computational Chemistry in Structure-Based Solute Carrier Transporter Drug Design: Recent Advances and Future Perspectives;Journal of Chemical Information and Modeling;2024-01-31
3. Prodrugs as empowering tools in drug discovery and development: recent strategic applications of drug delivery solutions to mitigate challenges associated with lead compounds and drug candidates;Chemical Society Reviews;2024
4. Neuropharmacology and neurotherapeutics;Biochemical and Molecular Pharmacology in Drug Discovery;2024
5. Study Models of Drug–Drug Interactions Involving P-Glycoprotein: The Potential Benefit of P-Glycoprotein Modulation at the Kidney and Intestinal Levels;Molecules;2023-11-10
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3