Sunitinib reduces tumor hypoxia and angiogenesis, and radiosensitizes prostate cancer stem-like cells

Author:

Diaz Roque1,Nguewa Paul A.12,Redrado Miriam1,Manrique Irene1,Calvo Alfonso13

Affiliation:

1. Division of Oncology; Center for Applied Medical Research (CIMA); University of Navarra; Pamplona Spain

2. Department of Microbiology and Parasitology; Instituto de Salud Tropical; University of Navarra; Pamplona Spain

3. Department of Histology and Pathology; University of Navarra; Pamplona Spain

Funder

UTE project CIMA. RTICC

FIS

Publisher

Wiley

Subject

Urology,Oncology

Reference49 articles.

1. Global cancer statistics;Jemal;CA Cancer J Clin,2011

2. The bone microenvironment in metastasis; what is special about bone?;Bussard;Cancer Metastasis Rev,2008

3. Bone metastasis in prostate cancer: Molecular and cellular mechanisms (Review);Ye;Int J Mol Med,2007

4. The role of tumor microenvironment in prostate cancer bone metastasis;Morrissey;J Cell Biochem,2007

5. Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases;Zhong;Cancer Res,1999

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