A rare case of non‐lupus full house nephropathy in a transplanted kidney, case report

Author:

Matarneh Ahmad Samir1ORCID,Salameh Omar2,Sardar Sundus1,Karasinski Amanda1,Channapragada Theja2,Abdulbasit Muhammad1,Washburn Erik3,Ghahramani Nasrollah1

Affiliation:

1. Department of Nephrology Penn State Milton S Hershey Medical Center Hershey Pennsylvania USA

2. Department of Internal Medicine Penn State Milton S Hershey Medical Center Hershey Pennsylvania USA

3. Department of Pathology Penn State Milton S Hershey Medical Center Hershey Pennsylvania USA

Abstract

Key Clinical MessageNon‐lupus full house nephropathy is a rare entity that is still poorly understood. It can complicate post‐transplant kidneys and result in a de novo process. Treatment is difficult but can be possibly achieved with optimization of immune suppression.AbstractNon‐lupus full house nephropathy is a rare entity with an unclear incidence. It describes the kidney biopsy findings of positive deposits for IgG, IgA, IgM, C3, and C1q on immunofluorescence in the absence of the classical diagnostic features of systemic lupus nephritis. This disease entity is becoming more recognized but further studies are still needed to evaluate the incidence, etiologies, and management of this condition. Transplant glomerulopathy is a major cause for renal graft loss. It can present with a wide variety of manifestations; it can cause AKI, CKD, or glomerular inflammations through an immune complex or autoimmune‐mediated damage.

Publisher

Wiley

Reference20 articles.

1. Non‐lupus full‐house nephropathy: a case series;Silva MD;J Bras Nefrol,2020

2. Pathogenesis of systemic lupus erythematosus

3. The Kidney Biopsy in Systemic Lupus Erythematosus: A View of the Past and a Vision of the Future

4. Incidence, timing, and risk factors for acute and chronic rejection;Neuberger J;Liver Transpl Surg,1999

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