Film measurement and analytical approach for assessing treatment accuracy and latency in a magnetic resonance‐guided radiotherapy system

Author:

Nakayama Hiroki12ORCID,Okamoto Hiroyuki1,Nakamura Satoshi1,Iijima Kotaro1ORCID,Chiba Takahito12,Takemori Mihiro12,Nakaichi Tetsu1ORCID,Mikasa Shohei1,Fujii Kyohei3,Sakasai Tatsuya4,Kuwahara Junichi14,Miura Yuki5,Fujiyama Daisuke4,Tsunoda Yuki4,Hanzawa Takuma4,Igaki Hiroshi6,Chang Weishan2

Affiliation:

1. Radiation Safety and Quality Assurance Division National Cancer Center Hospital Chuo‐ku Tokyo Japan

2. Department of Radiological Sciences Graduate School of Human Health Sciences Tokyo Metropolitan University, Higashioku Arakawa‐ku Tokyo Japan

3. Department of Radiation Sciences Komazawa University Setagaya‐ku Tokyo Japan

4. Department of Radiological Technology National Cancer Center Hospital Chuo‐ku Tokyo Japan

5. Department of Radiological Technology National Cancer Center Hospital East Kashiwa Chiba Japan

6. Department of Radiation Oncology National Cancer Center Hospital Chuo‐ku Tokyo Japan

Abstract

AbstractPurposeWe measure the dose distribution of gated delivery for different target motions and estimate the gating latency in a magnetic resonance‐guided radiotherapy (MRgRT) system.MethodThe dose distribution accuracy of the gated MRgRT system (MRIdian, Viewray) was investigated using an in‐house‐developed phantom that was compatible with the magnetic field and gating method. This phantom contains a simulated tumor and a radiochromic film (EBT3, Ashland, Inc.). To investigate the effect of the number of beam switching and target velocity on the dose distribution, two types of target motions were applied. One is that the target was periodically moved at a constant velocity of 5 mm/s with different pause times (0, 1, 3, 10, and 20 s) between the motions. During different pause times, different numbers of beams were switched on/off. The other one is that the target was moved at velocities of 3, 5, 8, and 10 mm/s without any pause (i.e., continuous motion). The gated method was applied to these motions at MRIdian, and the dose distributions in each condition were measured using films. To investigate the relation between target motion and dose distribution in the gating method, we compared the results of the gamma analysis of the calculated and measured dose distributions. Moreover, we analytically estimated the gating latencies from the dose distributions measured using films and the gamma analysis results.ResultsThe gamma pass rate linearly decreased with increasing beam switching and target velocity. The overall gating latencies of beam‐hold and beam‐on were 0.51 ± 0.17 and 0.35 ± 0.05 s, respectively.ConclusionsFilm measurements highlighted the factors affecting the treatment accuracy of the gated MRgRT system. Our analytical approach, employing gamma analysis on films, can be used to estimate the overall latency of the gated MRgRT system.

Funder

Japan Agency for Medical Research and Development

Publisher

Wiley

Subject

Radiology, Nuclear Medicine and imaging,Instrumentation,Radiation

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