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Substrate channeling between the human dihydrofolate reductase and thymidylate synthase

  • Published:2015-06-29 Issue:1 Volume:25 Page:79-86
  • ISSN:0961-8368
  • Container-title:Protein Science
  • language:en
  • Short-container-title:Protein Science

Author:

Wang Nuo1,McCammon J. Andrew123

Affiliation:

1. Department of Chemistry and Biochemistry; University of California San Diego; La Jolla California 92037

2. Department of Pharmacology; University of California San Diego; La Jolla California 92037

3. Howard Hughes Medical Institute, University of California San Diego; La Jolla California 92037

Funder

National Institutes of Health

National Science Foundation

National Biomedical Computation Resource

Howard Hughes Medical Institute

NSF Supercomputer Centers

Publisher

Wiley

Subject

Molecular Biology,Biochemistry

Reference57 articles.

1. Complexes of sequential metabolic enzymes;Srere;Annu Rev Biochem,1987

2. Channeling of substrates and intermediates in enzyme-catalyzed reactions;Huang;Annu Rev Biochem,2001

3. Williamson M. How proteins work Garland Science 338 344

4. Fundamental mechanisms of substrate channeling;Anderson;Methods Enzymol,1999

5. The molecular basis of substrate channeling;Miles;J Biol Chem,1999

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