TestDimorph: An R package for analysis of interpopulation sexual dimorphism differences using summary statistics

Author:

Abulnoor Bassam A.1ORCID,Attia MennattAllah Hassan2ORCID,Konigsberg Iain R.3ORCID,Konigsberg Lyle W.4ORCID

Affiliation:

1. Fixed prosthodontics Faculty of dentistry, Ain Shams University Cairo Egypt

2. Forensic medicine and clinical toxicology Faculty of medicine‐ Alexandria University Alexandria Egypt

3. Department of Biomedical Informatics University of Colorado School of Medicine Aurora Colorado USA

4. Department of Anthropology University of Illinois, at Urbana – Champaign Urbana Illinois USA

Abstract

AbstractObjectiveThe degree of sexual dimorphism in certain traits between males and females differ from one sample to another. Although trait differences by sex are often reported in bioanthropological research, few studies test for statistical significance or make raw data available. TestDimorph is the first R package dedicated to testing and comparing the degree of sexual dimorphism among different samples by leveraging summary statistics.Materials and MethodsWe provide two approaches of analysis of inter‐sample differences in degree of sexual dimorphism: univariate and multivariate for two or more samples. The methods follow upon publications primarily from the AJBA. Within‐sex size variability between samples is compared using one‐way ANOVA followed by control for multiple pairwise comparisons. In addition, we compute the overlapping area between the density functions of two normal distributions from the mixture intersection index or the non‐overlapping area using the dissimilarity index as well as Hedges' g with inferential support using the 95% confidence interval. Finally, we use a multivariate analysis of differences in patterning of sexual dimorphism between samples.ResultsWe demonstrate various results from applying TestDimorph functions to data supplied with the package.DiscussionThe package has many features including functionality for working with summary statistics, simulating data from summary statistics, and the extraction of summary statistics from raw data, so that the entire analysis can be performed through the package.

Publisher

Wiley

Subject

Paleontology,Archeology,Genetics,Anthropology,Anatomy,Epidemiology

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