Assessment of cellular and molecular metrics for dose selection in an in vivo comet assay: A case study with MDI
Author:
Affiliation:
1. The Dow Chemical Company, Toxicology & Environmental Research & Consulting Midland Michigan USA
Funder
Institute of Infection and Immunity
Publisher
Wiley
Subject
Health, Toxicology and Mutagenesis,Genetics (clinical),Epidemiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/em.22457
Reference30 articles.
1. Fourth International Workgroup on Genotoxicity testing: Results of the in vivo Comet assay workgroup
2. Mechanisms of cell injury and death
3. ECHA(2016) dossier for 4 4′‐methylenediphenyl diisocyanate; diphenylmethane‐4 4′‐diisocyanate. Available at:https://www.echa.europa.eu/web/guest/registration‐dossier/‐/registered‐dossier/15384/7/7/3/?documentUUID=fe6085f5‐4710‐4309‐9e1b‐1a9380159097.
4. Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells
5. Influence of experimental conditions on data variability in the liver comet assay
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