Targeted fusion analysis can aid in the classification and treatment of pediatric glioma, ependymoma, and glioneuronal tumors

Author:

Lake Jessica A.1ORCID,Donson Andrew M.2,Prince Eric3,Davies Kurtis D.4,Nellan Anandani2,Green Adam L.2ORCID,Mulcahy Levy Jean2,Dorris Kathleen2,Vibhakar Rajeev2,Hankinson Todd C.23,Foreman Nicholas K.2,Ewalt Mark D.4,Kleinschmidt‐DeMasters Bette K.5ORCID,Hoffman Lindsey M.2,Gilani Ahmed6

Affiliation:

1. Center for Cancer and Blood DisordersChildren's Hospital Colorado Aurora Colorado

2. The Morgan Adams Foundation Pediatric Brain Tumor Research ProgramDepartment of Pediatrics, Center for Cancer and Blood DisordersChildren's Hospital Colorado Aurora Colorado

3. Department of NeurosurgeryUniversity of Colorado Aurora Colorado

4. Department of PathologyUniversity of Colorado Aurora Colorado

5. Departments of Pathology, Neurology, NeurosurgeryUniversity of Colorado Aurora Colorado

6. Department of PathologyChildren's Hospital ColoradoUniversity of Colorado Aurora Colorado

Funder

University of Colorado Denver

National Cancer Institute

Morgan Adams Foundation

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology, and Child Health

Reference43 articles.

1. Cancer statistics, 2019

2. cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAFV600E mutation

3. Year 1 in the molecular era of pediatric brain tumor diagnosis: application of universal clinical targeted sequencing in an unselected cohort of children;Cole;JCO Precis Oncol,2018

4. Targeted Sequencing of Malignant Supratentorial Pediatric Brain Tumors Demonstrates a High Frequency of Clinically Relevant Mutations

5. Targeted next‐generation sequencing of pediatric neuro‐oncology patients improves diagnosis, identifies pathogenic germline mutations, and directs targeted therapy;Kline CN;Neuro Oncol,2017

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