Qualitative and Quantitative MR Imaging of the Cartilaginous Endplate: A Review

Author:

Wei Zhao12ORCID,Athertya Jiyo S.2,Chung Christine B.23,Bydder Graeme M.2,Chang Eric Y.23ORCID,Du Jiang234ORCID,Wenhui Yang15,Ma Yajun2

Affiliation:

1. Institute of Electrical Engineering Chinese Academy of Sciences Beijing China

2. Department of Radiology University of California San Diego San Diego California USA

3. Radiology Service Veterans Affairs San Diego Healthcare System San Diego California USA

4. Department of Bioengineering University of California San Diego San Diego California USA

5. University of Chinese Academy of Sciences Beijing China

Abstract

The cartilaginous endplate (CEP) plays a pivotal role in facilitating the supply of nutrients and, transport of metabolic waste, as well as providing mechanical support for the intervertebral disc (IVD). Recent technological advances have led to a surge in MR imaging studies focused on the CEP. This article describes the anatomy and functions of the CEP as well as MRI techniques for both qualitative and quantitative assessment of the CEP. Effective CEP MR imaging sequences require two key features: high spatial resolution and relatively short echo time. High spatial resolution spoiled gradient echo (SPGR) and ultrashort echo time (UTE) sequences, fulfilling these requirements, are the basis for most of the sequences employed in CEP imaging. This article reviews existing sequences for qualitative CEP imaging, such as the fat‐suppressed SPGR and UTE, dual‐echo subtraction UTE, inversion recovery prepared and fat‐suppressed UTE, and dual inversion recovery prepared UTE sequences. These sequences are employed together with other techniques for quantitative CEP imaging, including measurements of T2*, T2, T1, T1ρ, magnetization transfer, perfusion, and diffusion tensor parameters.Evidence Level1Technical EfficacyStage 2

Funder

National Institutes of Health

GE Healthcare

Publisher

Wiley

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