Effects of pyruvate dose on in vivo metabolism and quantification of hyperpolarized 13 C spectra

Author:

Janich M. A.123,Menzel M. I.2,Wiesinger F.2,Weidl E.3,Khegai O.12,Ardenkjaer-Larsen J. H.4,Glaser S. J.1,Haase A.5,Schulte R. F.2,Schwaiger M.3

Affiliation:

1. Technische Universität München; Chemistry; Munich Germany

2. GE Global Research; Munich Germany

3. Technische Universität München; Nuclear Medicine; Munich Germany

4. GE Healthcare; MST-ASL MR; Copenhagen Denmark

5. Technische Universität München; Medical Engineering; Munich Germany

Funder

BMBF MOBITUM

Publisher

Wiley

Subject

Spectroscopy,Radiology, Nuclear Medicine and imaging,Molecular Medicine

Reference35 articles.

1. Increase in signal-to-noise ratio of >10,000 times in liquid-state NMR;Ardenkjaer-Larsen;Proc. Natl. Acad. Sci. USA,2003

2. Real-time metabolic imaging;Golman;Proc. Natl. Acad. Sci. USA,2006

3. Biomedical applications of hyperpolarized 13C magnetic resonance imaging;Gallagher;Prog. Nucl. Magn. Reson. Spectrosc.,2009

4. Positron emission tomography as an imaging biomarker;Weber;J. Clin. Oncol.,2006

5. The effect of hyperpolarized tracer concentration on myocardial uptake and metabolism;Schroeder;Magn. Reson. Med.,2009

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