Applications of Plasma‐Rich Plasma, Exosomes, and Stem Cells in Aesthetics: A Narrative Review

Author:

Ablon Glynis1ORCID,Smith Zoë Indigo2ORCID,Munavalli Girish (Gilly)34ORCID

Affiliation:

1. UCLA Department of Dermatology Ablon Skin Institute and Research Center Manhattan Beach California USA

2. Department of Dermatology UCLA School of Medicine Dermatology Los Angeles California USA

3. Department of Dermatology Wake Forest University School of Medicine Winston‐Salem North Carolina USA

4. Laser, and Vein Specialists of the Carolinas Charlotte North Carolina USA

Abstract

ABSTRACTIntroductionPlasma‐rich plasma (PRP), exosomes, and stem cells represent promising new treatments for facial rejuvenation and to enhance other cosmetic procedures. Although these treatments are rapidly advancing, there are no universally accepted treatment protocols for their use. The goal of the following review is to describe some of the possible benefits of PRP, exosomes, and stem cells in aesthetic medicine.ResultsA review of available studies showed that potential uses of PRP include wound healing after facial surgery, facial rejuvenation, androgenetic alopecia, acne scars, striae distensae, and vitiligo. Exosomes may provide beneficial treatment for skin rejuvenation, scar reduction, hyperpigmentation, and hair growth. Stem cells show promise for androgenetic alopecia, scar improvement, and treatment of photoaged skin. These new technologies may be used alone, but are often combined with existing aesthetic treatments.ConclusionPRP, exosomes, and stem cells may play an important role in restoring youthful tissue structure and function. Interpretation of some study results is sometimes challenged by the lack of standardized treatment protocols, including routes of application and dosing. When combined with other devices and techniques, results are sometime unclear as to which treatment plays the greater role.

Publisher

Wiley

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