Metabolite identification of triptolide by data-dependent accurate mass spectrometric analysis in combination with online hydrogen/deuterium exchange and multiple data-mining techniques-Reference-Cited by-同舟云学术

Metabolite identification of triptolide by data-dependent accurate mass spectrometric analysis in combination with online hydrogen/deuterium exchange and multiple data-mining techniques

Published:2011-09-26 Issue:20 Volume:25 Page:3167-3177
ISSN:0951-4198
Container-title:Rapid Communications in Mass Spectrometry
language:en
Short-container-title:Rapid Commun. Mass Spectrom.

Author:

Du Fuying¹,Liu Ting²,Liu Tian¹,Wang Yongwei²,Wan Yakun³,Xing Jie¹

Affiliation:

1. School of Pharmaceutical Sciences; Shandong University; Jinan; China

2. Thermo Fisher Scientific; Shanghai; China

3. The Laboratory of Developmental Genes and Human Diseases; Southeast University; Nanjing; China

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Analytical Chemistry

Reference16 articles.

1. Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. 2. Rheumatoid arthritis;Cameron;Phytother. Res.,2009

2. Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats;Liu;Toxicology,2010

3. Pharmacokinetic study of triptolide, a constituent of immunosuppressive Chinese herb medicine, in rats;Shao;Biol. Pharm. Bull.,2007

4. Characterization of triptolide hydroxylation by cytochrome P450 in human and rat liver microsomes;Li;Xenobiotica,2008

5. Effects of cytochrome P4503A inducer dexamethasone on the metabolism and toxicity of triptolide in rat;Ye;Toxicol. Lett.,2010

Cited by 21 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Antitumor mechanisms and future clinical applications of the natural product triptolide;Cancer Cell International;2024-04-27

2. Metabolic Activation of the Toxic Natural Products From Herbal and Dietary Supplements Leading to Toxicities;Frontiers in Pharmacology;2021-10-20

3. Identification of the chemical components and metabolites of tripterygium glycoside tablets in mice by HPLC-Q/TOF MS;Journal of Chromatography B;2019-09

4. Preclinical Pharmacokinetics of Triptolide: A Potential Antitumor Drug;Current Drug Metabolism;2019-04-30

5. Identification of hepatotoxic and nephrotoxic potential markers of triptolide in mice with delayed-type hypersensitivity;Journal of Pharmaceutical and Biomedical Analysis;2018-10