The synthesis of [carboxamido-14C]SAR240550, [carboxamido-14C]Iniparib, via monocarboxylation of 1,4-diiodobenzene-Reference-Cited by-同舟云学术

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The synthesis of [carboxamido-14C]SAR240550, [carboxamido-14C]Iniparib, via monocarboxylation of 1,4-diiodobenzene

Published:2012-11-27 Issue:14 Volume:55 Page:497-498
ISSN:0362-4803
Container-title:Journal of Labelled Compounds and Radiopharmaceuticals
language:en
Short-container-title:J. Label Compd. Radiopharm

Author:

Gregson Thomas J.¹,Kohler Andrew D.¹,Spurr Daniel W.¹

Affiliation:

1. Sanofi-Aventis; Isotope Chemistry and Metabolite Synthesis; Willowburn Ave.; Alnwick; Northumberland; NE66 2JH; UK

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology, Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference22 articles.

1. Efficacy of BSI-201, a poly (ADP-ribose) polymerase-1 (PARP1) inhibitor, in combination with gemcitabine/carboplatin (G/C) in patients with metastatic triple-negative breast cancer (TNBC): Results of a randomized phase II trial

2. Systematic Survey of Therapeutic Trials for Metastatic Colorectal Cancer: Room for Improvement in the Critical Pathway

3. A phase IB study evaluating BSI-201 in combination with chemotherapy in subjects with advanced solid tumors

4. Anti-cancer action of 4-iodo-3-nitrobenzamide in combination with buthionine sulfoximine: inactivation of poly(ADP-ribose) polymerase and tumor glycolysis and the appearance of a poly(ADP-ribose) polymerase protease

5. Potential chemotherapeutic activity of 4-iodo-3-nitrobenzamide

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