Human umbilical cord blood-derived mesenchymal stem cells improve functional recovery through thrombospondin1, pantraxin3, and vascular endothelial growth factor in the ischemic rat brain

Author:

Park Hyung Woo123,Moon Hyo-Eun123,Kim Hye-Soo R.123,Paek Seung Leal1234,Kim Yona123,Chang Jong Wook5,Yang Yoon Sun6,Kim KwanWoo123,Oh Wonil6,Hwang Jae Ha123,Kim Jin Wook123,Kim Dong Gyu123,Paek Sun Ha123

Affiliation:

1. Department of Neurosurgery; Seoul National University College of Medicine; Seoul Korea

2. Cancer Research Institute, Seoul National University College of Medicine; Seoul Korea

3. Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine; Seoul Korea

4. Department of Neurosurgery; Mayo Clinic; Rochester Minnesota

5. Stem Cell & Regenerative Medicine Center, Research Institute for Future Medicine; Samsung Medical Center; Seoul Korea

6. Biomedical Research Institute, Medipost Co., Ltd.; Seoul Korea

Funder

Korea Institute of Planning & Evaluation for Technology in Food, Agriculture, Forestry, and Fisheries, Republic of Korea

Korea Healthcare Technology R&D Project, Ministry of Health & Welfare, Republic of Korea

Publisher

Wiley

Subject

Cellular and Molecular Neuroscience

Reference51 articles.

1. Multipotent adult progenitor cells sustain function of ischemic limbs in mice;Aranguren;J Clin Invest,2008

2. Intraventricular vascular endothelial growth factor antibody increases infarct volume following transient cerebral ischemia;Bao;Zhongguo Yao Li Xue Bao (Acta Pharmacol Sin),1999

3. The pattern recognition receptor PTX3 is recruited at the synapse between dying and dendritic cells, and edits the cross-presentation of self, viral, and tumor antigens;Baruah;Blood,2006

4. Thrombospondin-1 binds to ApoER2 and VLDL receptor and functions in postnatal neuronal migration;Blake;EMBO J,2008

5. Therapeutic benefit of intracerebral transplantation of bone marrow stromal cells after cerebral ischemia in rats;Chen;J Neurol Sci,2001a

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