No evidence that G6PD deficiency affects the efficacy or safety of daunorubicin in acute lymphoblastic leukemia induction therapy

Author:

Robinson Katherine M.1,Yang Wenjian1,Karol Seth E.2,Kornegay Nancy1,Jay Dennis3,Cheng Cheng4,Choi John K.3,Campana Dario5,Pui Ching‐Hon2ORCID,Wood Brent6,Borowitz Michael J.7,Gastier‐Foster Julie8,Larsen Eric C.9,Winick Naomi10,Carroll William L.11ORCID,Loh Mignon L.12,Raetz Elizabeth A.11,Hunger Stephen P.13,Devidas Meenakshi14,Mardis Elaine R.8,Fulton Robert S.15,Relling Mary V.1ORCID,Jeha Sima2

Affiliation:

1. Department of Pharmaceutical SciencesSt. Jude Children's Research Hospital Memphis Tennessee

2. Department of OncologySt. Jude Children's Research Hospital Memphis Tennessee

3. Department of PathologySt. Jude Children's Research Hospital Memphis Tennessee

4. Department of BiostatisticsSt. Jude Children's Research Hospital Memphis Tennessee

5. Department of PaediatricsNational University of Singapore Singapore

6. Department of Laboratory MedicineSeattle Children's Hospital Seattle Washington

7. Department of Hematologic PathologyJohn's Hopkins University Baltimore Maryland

8. Nationwide Children's HospitalThe Ohio State University Columbus Ohio

9. Department of Pediatric Hematology‐OncologyMaine Medical Center Scarborough Maine

10. Department of PediatricsUT Southwestern Medical Center Dallas Texas

11. Perlmutter Cancer CenterDepartment of PediatricsNYU Langone Medical Center New York City New York

12. Department of PediatricsBenioff Children's Hospital and the Helen Diller Family Comprehensive Cancer CenterUniversity of California San Francisco San Francisco California

13. Department of PediatricsChildren's Hospital of Philadelphia Philadelphia Pennsylvania

14. Department of BiostatisticsUniversity of Florida Gainesville Florida

15. Department of GeneticsWashington University School of Medicine St. Louis Missouri

Funder

National Institutes of Health

St. Baldrick's Foundation

American Lebanese Syrian Associated Charities

Publisher

Wiley

Subject

Oncology,Hematology,Pediatrics, Perinatology and Child Health

Reference20 articles.

1. Adriamycin and daunomycin generate reactive oxygen compounds in erythrocytes;Henderson CA;Blood,1978

2. The effect of BCNU and adriamycin on normal and G6PD deficient erythrocytes

3. Oxidant Stress and Haemolysis of the Human Erythrocyte

4. Medications and Glucose-6-Phosphate Dehydrogenase Deficiency

5. The Metabolic and Molecular Bases of Inherited Disease 2001 McGraw‐Hill New York City LMA Luzzatto A Mehta T Vulliamy AL Beaudet CR Scriver WS Sly D Valle Chapter 179: Glucose 6‐phosphate dehydrogenase deficiency 4517‐4553

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