Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage-Reference-Cited by-同舟云学术

Cancer-associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse-strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage

Published:2013-01-25 Issue:3 Volume:229 Page:400-409
ISSN:0022-3417
Container-title:The Journal of Pathology
language:en
Short-container-title:J. Pathol.

Author:

Anglesio MS¹,Wang Y¹,Yang W²,Senz J¹,Wan A³,Heravi-Moussavi A¹,Salamanca C¹,Maines-Bandiera S¹,Huntsman DG¹²,Morin GB⁴⁵

Affiliation:

1. Department of Pathology and Laboratory Medicine; University of British Columbia; Vancouver Canada

2. Centre for Translational and Applied Genomics (CTAG); British Columbia Cancer Agency; Vancouver Canada

3. Department of Molecular Oncology; British Columbia Cancer Agency Cancer Research Centre; Vancouver Canada

4. Michael Smith Genome Sciences Centre; British Columbia Cancer Agency; Vancouver Canada

5. Department of Medical Genetics; University of British Columbia; Vancouver Canada

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/path.4135/fullpdf

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