Quantitation of P450 3A4 endogenous biomarker - 4β-hydroxycholesterol - in human plasma using LC/ESI-MS/MS-Reference-Cited by-同舟云学术

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Quantitation of P450 3A4 endogenous biomarker - 4β-hydroxycholesterol - in human plasma using LC/ESI-MS/MS

Published:2014-05-25 Issue:6 Volume:28 Page:794-801
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomed. Chromatogr.

Author:

Huang Mike-Qingtao¹,Lin Weisheng²,Wang Weimin²,Zhang Wei²,Lin Zhongping John²,Weng Naidong¹

Affiliation:

1. Janssen Research and Development LLC; Pharmaceutical Companies of Johnson & Johnson; 1400 McKean Road Spring House PA 19477 USA

2. Frontage Laboratories Inc.; 700 Pennsylvania Drive Exton PA 19341 USA

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference24 articles.

1. Comparison of endogenous 4β-hydroxycholesterol with midazolam as markers for CYP3A4 induction by rifampicin;Björkhem-Bergman;Drug Metabolism and Disposition,2013

2. Antiepileptic drugs increase plasma levels of 4β-hydroxycholesterol in humans. Evidence for involvement of cytochrome P450 3A4;Bodin;Journal of Biological Chemistry,2001

3. Recommendations for the bioanalytical method validation of ligand-binding assays to support pharmacokinetic assessments of macromolecules;DeSilva;Pharmaceutical Research,2003

4. Analysis of cholesterol oxidation products in biological samples;Diczfalusy;Journal of AOAC International,2004

5. 4β-Hydroxycholesterol, an endogenous marker of CYP3A4/5 activity in humans;Diczfalusy;British Journal of Clinical Pharmacology,2011

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A cutting-edge approach based on UHPLC-MS to simultaneously investigate oxysterols and cholesterol precursors in biological samples: Validation in Huntington's disease mouse model;Talanta Open;2024-08

2. Gene Polymorphisms of NLRP3 Associated With Plasma Levels of 4β‐Hydroxycholesterol, an Endogenous Marker of CYP3A Activity, in Patients With Asthma;Clinical Pharmacology & Therapeutics;2024-03-14

3. Sensitive UHPLC-MS/MS quantification method for 4β- and 4α-hydroxycholesterol in plasma for accurate CYP3A phenotyping;Journal of Lipid Research;2022-03

4. Quantitative analysis of 4β- and 4α‑hydroxycholesterol in human plasma and serum by UHPLC/ESI-HR-MS;Journal of Chromatography B;2018-11

5. Chromatography of oxysterols;Biochimie;2018-10

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