Testosterone accumulation in prostate cancer cells is enhanced by facilitated diffusion

Author:

Kaipainen Arja1,Zhang Ailin1,Gil da Costa Rui M.1,Lucas Jared1,Marck Brett2,Matsumoto Alvin M.2,Morrissey Colm3,True Lawrence D.4,Mostaghel Elahe A.256,Nelson Peter S.156

Affiliation:

1. Division of Human BiologyFred Hutchinson Cancer Research CenterSeattle Washington

2. Geriatric Research, Education and Clinical CenterVA Puget Sound Health Care SystemSeattle Washington

3. Department of UrologyUniversity of WashingtonSeattle Washington

4. Department of PathologyUniversity of WashingtonSeattle Washington

5. Clinical Research DivisionFred Hutchinson Cancer Research CenterSeattle Washington

6. Department of MedicineUniversity of WashingtonSeattle Washington

Funder

Ohio Department of Development

National Institutes of Health

Publisher

Wiley

Subject

Urology,Oncology

Reference67 articles.

1. Studies on prostatic cancer. I. The effect of castration, of oestrogen and of androgen injections onserum phosphatases in metastatic carcinoma of the prostate;Huggins C;Cancer Res,1941

2. Androgen deprivation therapy in the treatment of advanced prostate cancer;Perlmutter MA;Rev Urol,2007

3. The Androgen Axis in Recurrent Prostate Cancer

4. Testosterone and Dihydrotestosterone Tissue Levels in Recurrent Prostate Cancer

5. Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth

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