Inhibition of farnesyl protein transferase sensitizes human MCF-7 breast cancer cells to roscovitine-mediated cell cycle arrest
Author:
Publisher
Wiley
Subject
Cell Biology,Molecular Biology,Biochemistry
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1. BAI, a novel Cdk inhibitor, enhances farnesyltransferase inhibitor LB42708-mediated apoptosis in renal carcinoma cells through the downregulation of Bcl-2 and c-FLIP (L);International Journal of Oncology;2014-07-04
2. Synthesis and Ligand Based 3D-QSAR of 2,3-Bis-benzylidenesuccinaldehyde Derivatives as New Class Potent FPTase Inhibitor, and Prediction of Active Molecules;Bulletin of the Korean Chemical Society;2010-05-20
3. PNUTS knockdown potentiates the apoptotic effect of Roscovitine in breast and colon cancer cells;International Journal of Oncology;2010-03-24
4. Synergistic combinations of signaling pathway inhibitors: Mechanisms for improved cancer therapy;Drug Resistance Updates;2009-06
5. A combined treatment of HeLa cells with the farnesyl protein transferase inhibitor L-744,832 and cisplatin significantly increases the therapeutic effect as compared to cisplatin monotherapy;Journal of Cellular Biochemistry;2008
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