Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening-Reference-Cited by-同舟云学术

Deciphering the pathogenic role of a variant with uncertain significance for short QT and Brugada syndromes using gene‐edited human‐induced pluripotent stem cell‐derived cardiomyocytes and preclinical drug screening

Published:2021-12 Issue:12 Volume:11 Page:
ISSN:2001-1326
Container-title:Clinical and Translational Medicine
language:en
Short-container-title:Clinical & Translational Med

Author:

El‐Battrawy Ibrahim¹²³^ORCID,Lan Huan⁴,Cyganek Lukas⁵²,Maywald Lasse¹²,Zhong Rujia¹,Zhang Feng¹,Xu Qiang¹,Lee Jihyun⁶,Duperrex Eliane⁶,Hierlemann Andreas⁶,Saguner Ardan M.⁷,Duru Firat⁷,Kovacs Boldizsar⁷,Huang Mengying¹,Liao Zhenxing¹,Albers Sebastian¹²,Müller Jonas¹²,Dinkel Hendrik¹²,Rose Lena¹,Hohn Alyssa¹,Yang Zhen¹,Qiao Lin¹,Li Yingrui¹,Lang Siegfried¹²,Kleinsorge Mandy⁵⁷,Mügge Andreas³,Aweimer Assem³,Fan Xuehui¹,Diecke Sebastian⁸,Akin Ibrahim¹²,Li Guang⁴,Zhou Xiaobo¹⁴²

Affiliation:

1. First Department of Medicine Faculty of Medicine University Medical Centre Mannheim (UMM), University of Heidelberg Mannheim Germany

2. DZHK (German Center for Cardiovascular Research) Partner Site Heidelberg‐Mannheim and Göttingen Mannheim Germany

3. Department of Cardiology and Angiology Bergmannsheil Bochum, Medical Clinic II Ruhr University Bochum Germany

4. Key Laboratory of Medical Electrophysiology of Ministry of Education and Medical Electrophysiological Key Laboratory of Sichuan Province Institute of Cardiovascular Research, Southwest Medical University Luzhou China

5. Stem Cell Unit, Clinic for Cardiology and Pneumology University Medical Center Göttingen Göttingen Germany

6. Department of Biosystems Science and Engineering Bioengineering Laboratory Basel Switzerland

7. Department of Cardiology Electrophysiology Division University Heart Center Zurich Zurich Switzerland

8. Max Delbrück Center for Molecular Medicine Berlin Germany

Publisher

Wiley

Subject

Molecular Medicine,Medicine (miscellaneous)

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/ctm2.646

Reference10 articles.

1. QT interval variables from 24 hour electrocardiography and the two year risk of sudden death.