The vitamin D receptor agonist elocalcitol inhibits IL-8-dependent benign prostatic hyperplasia stromal cell proliferation and inflammatory response by targeting the RhoA/Rho kinase and NF-kB pathways

Author:

Penna Giuseppe,Fibbi Benedetta,Amuchastegui Susana,Corsiero Elisa,Laverny Gilles,Silvestrini Enrico,Chavalmane Aravinda,Morelli Annamaria,Sarchielli Erica,Vannelli Gabriella Barbara,Gacci Mauro,Colli Enrico,Maggi Mario,Adorini Luciano

Funder

European Community grant NucSys

Publisher

Wiley

Subject

Urology,Oncology

Reference67 articles.

1. Benign prostatic hyperplasia;Webber;Clin Evid,2006

2. Molecular and cellular pathogenesis of benign prostatic hyperplasia;Lee;J Urol,2004

3. Expression and cellular localization of keratinocyte growth factor and its receptor in human hyperplastic prostate tissue;De Bellis;J Clin Endocrinol Metab,1998

4. FGF7 and FGF2 are increased in benign prostatic hyperplasia and are associated with increased proliferation;Ropiquet;J Urol,1999

5. Interleukin-8 is a paracrine inducer of fibroblast growth factor 2, a stromal and epithelial growth factor in benign prostatic hyperplasia;Giri;Am J Pathol,2001

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