Solution conformations and hydrolytic stability of 2′ - and 3′ -substituted 2′,3′-dideoxyribonucleosides, including some potential inhibitors of human immunodeficiency virus-Reference-Cited by-同舟云学术

Solution conformations and hydrolytic stability of 2′ - and 3′ -substituted 2′,3′-dideoxyribonucleosides, including some potential inhibitors of human immunodeficiency virus

Published:1992-11 Issue:11 Volume:5 Page:741-747
ISSN:0894-3230
Container-title:Journal of Physical Organic Chemistry
language:en
Short-container-title:J. Phys. Org. Chem.

Author:

Oksman Pentti,Hakala Harri,Zavgorodny Sergei,Polianski Michael,Azhayev Alex,van Aerschot Arthur,Herdewijn Piet,Lönnberg Harri

Publisher

Wiley

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference58 articles.

1. 3'-Azido-3'-deoxythymidine (BW A509U): an antiviral agent that inhibits the infectivity and cytopathic effect of human T-lymphotropic virus type III/lymphadenopathy-associated virus in vitro.

2. Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides.

3. 3'-Substituted 2',3'-dideoxynucleoside analogs as potential anti-HIV (HTLV-III/LAV) agents

4. Investigations on the anti-HIV activity of 2′, 3′-dideoxyadenosine analogues with modifications in either the pentose or purine moiety

5. Synthesis and antiviral activity of various 3'-azido, 3'-amino, 2',3'-unsaturated, and 2',3'-dideoxy analogs of pyrimidine deoxyribonucleosides against retroviruses

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1. Assignment of the 1H, 19F, and 13C NMR spectra of 2-deoxy-2-fluoro-d-ribose and characterisation of the isomeric equilibrium;Carbohydrate Research;1996-04

2. Synthesis of a 2,3-dideoxy-2,3-difluorofuranose with the d-lyxo configuration. An intramolecular rearrangement of methyl 5-O-benzoyl-2,3-dideoxy-2,3-difluoro-d-lyxofuranoside observed during the attempted synthesis of 1-(2,3-dideoxy-2,3-difluoro-β-d-lyxofuranosyl)thymine;Carbohydrate Research;1994-09

3. Synthesis of 3′-fluoromethylthio-, 3′-fluoromethylsulfinyl- and 3′-fluoromethylsulfonyl-substituted 3′-deoxythymidine;J. Chem. Soc., Perkin Trans. 1;1994