Methods and clinical biomarker discovery for targeted proteomics using Olink technology-Reference-Cited by-同舟云学术

Methods and clinical biomarker discovery for targeted proteomics using Olink technology

Published:2024-05-10 Issue: Volume: Page:
ISSN:1862-8346
Container-title:PROTEOMICS – Clinical Applications
language:en
Short-container-title:Proteomics Clinical Apps

Author:

Wang Han¹²,Zhao Tian¹²,Zeng Jingjing¹²,Zhang Ruijie¹²,Pu Liyuan¹²,Qian Suying³,Xu Shan⁴,Jiang Yannan¹²,Pan Lifang¹²,Dai Xiaoyu⁵,Guo Xu⁶,Han Liyuan¹²^ORCID

Affiliation:

1. Department of Clinical Epidemiology Ningbo No. 2 Hospital Ningbo Zhejiang China

2. Center for Cardiovascular and Cerebrovascular Epidemiology and Translational Medicine, Ningbo Institute of Life and Health Industry University of Chinese Academy of Sciences Ningbo Zhejiang China

3. Key Laboratory of Diagnosis and Treatment of Digestive System Tumors of Zhejiang Province Ningbo No.2 Hospital Ningbo Zhejiang China

4. Shen zhen Nanshan Center for Chronic Disease Control Shenzhen Guangdong China

5. Department of Anus & Intestine Surgery Ningbo No.2 Hospital Ningbo Zhejiang China

6. Department of Rehabilitation Medicine Ningbo No.2 Hospital Ningbo Zhejiang China

Abstract

AbstractPurposeThis paper is to offer insights for designing research utilizing Olink technology to identify biomarkers and potential therapeutic targets for disease treatment.Experimental DesignWe discusses the application of Olink technology in oncology, cardiovascular, respiratory and immune‐related diseases, and Outlines the advantages and limitations of Olink technology.ResultsOlink technology simplifies the search for therapeutic targets, advances proteomics research, reveals the pathogenesis of diseases, and ultimately helps patients develop precision treatments.ConclusionsAlthough proteomics technology has been rapidly developed in recent years, each method has its own disadvantages, so in the future research, more methods should be selected for combined application to verify each other.

Funder

Medical Scientific Research Foundation of Zhejiang Province, China

Natural Science Foundation of Guangdong Province

National Natural Science Foundation of China

Publisher

Wiley

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/prca.202300233

Reference109 articles.

1. Recent Advances in Proteomics-Based Approaches to Studying Age-Related Macular Degeneration: A Systematic Review

2. Homogeneous and digital proximity ligation assays for the detection of Clostridium difficile toxins A and B

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