Prognostic and mechanistic potential of progesterone sulfates in intrahepatic cholestasis of pregnancy and pruritus gravidarum

Author:

Abu-Hayyeh Shadi1,Ovadia Caroline1,Lieu TinaMarie2,Jensen Dane D.2,Chambers Jenny13,Dixon Peter H.13,Lövgren-Sandblom Anita4,Bolier Ruth5,Tolenaars Dagmar5,Kremer Andreas E.56,Syngelaki Argyro7,Noori Muna3,Williams David8,Marin Jose J.G.9,Monte Maria J.9,Nicolaides Kypros H.7,Beuers Ulrich5,Oude-Elferink Ronald5,Seed Paul T.1,Chappell Lucy1,Marschall Hanns-Ulrich10,Bunnett Nigel W.211,Williamson Catherine13

Affiliation:

1. Women's Health Academic Centre; King's College London; London United Kingdom

2. Monash Institute of Pharmaceutical Sciences and Australian Research Council Centre of Excellence in Convergent Bio-Nano Science and Technology; Monash University; Parkville Victoria Australia

3. Institute of Reproductive and Developmental Biology; Imperial College London; London United Kingdom

4. Department of Clinical Chemistry; Karolinska University Hospital Huddinge; Stockholm Sweden

5. Tytgat Institute for Liver and Intestinal Research; Academic Medical Centre; Amsterdam The Netherlands

6. Department of Medicine 1; Friedrich-Alexander-University of Erlangen-Nuremberg; Erlangen Germany

7. Harris Birthright Research Centre for Fetal Medicine; King's College Hospital; London United Kingdom

8. Institute for Women's Health; University College London Hospitals; London United Kingdom

9. Laboratory of Experimental Hepatology and Drug Targeting (HEVEFARM), Biomedical Research Institute of Salamanca (IBSAL); University of Salamanca, National Institute for the Study of Liver and Gastrointestinal Diseases (CIBERehd); Salamanca Spain

10. Institute of Medicine, Department of Molecular and Clinical Medicine; University of Gothenburg; Gothenburg Sweden

11. Department of Pharmacology; University of Melbourne; Parkville Victoria Australia

Funder

Wellcome Trust

National Institute of Health Research Biomedical Research Centre at Guy's and St Thomas NHS Foundation Trust and King's College London

National Health and Medical Research Council

Australian Research Council, and Monash University

Publisher

Wiley

Subject

Hepatology

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