Novel, linked bioreactor system for continuous production of biologics
Author:
Affiliation:
1. Culture Process DevelopmentPfizer IncAndover Massachusetts
2. Upstream Process DevelopmentAkston BiosciencesBeverly Massachusetts
3. Department of Process ScienceBoehringer IngelheimFremont California
Funder
Boehringer Ingelheim
Pfizer
Publisher
Wiley
Subject
Applied Microbiology and Biotechnology,Bioengineering,Biotechnology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/bit.26985
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1. Uncoupling of cell growth and proliferation results in enhancement of productivity in p21CIP1-arrested CHO cells
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4. Perfusion Processes
5. Very high density of Chinese hamster ovary cells in perfusion by alternating tangential flow or tangential flow filtration in WAVE bioreactor™—part II: Applications for antibody production and cryopreservation
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