Affiliation:
1. Institute of Radiology University Hospital Erlangen, Friedrich‐Alexander‐Universität Erlangen‐Nürnberg (FAU) Erlangen Germany
Abstract
PurposeStudies on intravoxel incoherent motion (IVIM) imaging in the liver have been carried out with different acquisition protocols. The number of acquired slices and the distances between slices can influence IVIM measurements due to saturation effects, but these effects have often been disregarded. This study investigated differences in biexponential IVIM parameters between two slice settings.MethodsFifteen healthy volunteers (21–30 years) were examined at a field strength of 3 T. Diffusion‐weighted images of the abdomen were acquired with 16 b values (0–800 s/mm2), with four slices for the few slices setting and 24–27 slices for the many slices setting. Regions of interest were manually drawn in the liver. The data were fitted with a monoexponential signal curve and a biexponential IVIM curve, and biexponential IVIM parameters were determined. The dependence on the slice setting was assessed with Student's t test for paired samples (normally distributed IVIM parameters) and the Wilcoxon signed‐rank test (non‐normally distributed parameters).ResultsNone of the parameters were significantly different between the settings. For few slices and many slices, respectively, the mean values (SDs) for
were
() and
(); for
they were 29.7% (6.2%) and 27.7% (3.6%); and for
they were
() and
().ConclusionBiexponential IVIM parameters in the liver are comparable among IVIM studies that use different slice settings, with mostly negligible saturation effects. However, this may not hold for studies that use much shorter TR.
Funder
Deutsche Forschungsgemeinschaft
Subject
Radiology, Nuclear Medicine and imaging
Cited by
1 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献