Simulated annealing exploration of an active-site tyrosine in TEM-1β-lactamase suggests the existence of alternate conformations
Author:
Publisher
Wiley
Subject
Molecular Biology,Biochemistry,Structural Biology
Reference41 articles.
1. Evolution and dissemination of β-lactamases accelerated by generations of β-lactam antibiotics;Medeiros;Clin Infect Dis,1997
2. Inactivation of antibiotics and the dissemination of resistance genes;Davies;Science,1994
3. Penicillinase synthesis controlled by infectious R factors in Enterobacteriaceae;Datta;Nature,1965
4. Predicting the evolution of antibiotic resistance genes;Hall;Nat Rev Microbiol,2004
5. Predicting the emergence of antibiotic resistance by directed evolution and structural analysis;Orencia;Nat Struct Biol,2001
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