Highly efficient synthesis of [11C]S12968 and [11C]S12967, for thein vivo imaging of the cardiac calcium channels using PET

Author:

Dolle Fr�d�ric,Valette H�ric,Hinnen Fran�oise,Demphel St�phane,Bramoulle Yann,Peglion Jean-Louis,Crouzel Christian

Publisher

Wiley

Subject

Organic Chemistry,Spectroscopy,Drug Discovery,Radiology Nuclear Medicine and imaging,Biochemistry,Analytical Chemistry

Reference18 articles.

1. Calcium Entry Blockers and Activators: Conformational and Structural Determinants of Dihydropyrimidine Calcium Channel Modulators

2. (ADIR et Cie). Novel 1,4-dihydropyridines derivatives, their process of preparation and pharmaceutical compositions containing them. EP259206, FR2602231, JP88041460, US4870090.

3. (ADIR et Cie). 1,4-Dihydropyridines derivative, named (minus;)-2-((2-aminoethoxy) ethoxy) methyl-4-(2,3-dichlorophenyl) 3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine, process for its preparation and pharmaceutical compositions containing it. AU892390, EP4065502, FR2649395.

4. Ca2+Channel inhibition by a new dihydropyridine derivatives,S111568 and its enantiomers S12967 and S12968

5. Inhibition of L-Type But Not T-Type Calcium Channel Current by a New Dihydropyridine Derivative, S11568

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