Bone morphogenetic protein-2 release profile modulates bone formation in phosphorylated hydrogel

Author:

Olthof Maurits G.L.1234ORCID,Kempen Diederik H.R.5,Liu Xifeng12,Dadsetan Mahrokh12,Tryfonidou Marianna A.3,Yaszemski Michael J.12,Dhert Wouter J.A.34,Lu Lichun12

Affiliation:

1. Department of Physiology and Biomedical Engineering; Mayo Clinic College of Medicine; Rochester MN USA

2. Department of Orthopedic Surgery; Mayo Clinic College of Medicine; Rochester MN USA

3. Faculty of Veterinary Medicine; Utrecht University; Utrecht The Netherlands

4. Department of Orthopaedics; University Medical Center; Utrecht The Netherlands

5. Department of Orthopaedic Surgery; Onze Lieve Vrouwe Gasthuis; Amsterdam The Netherlands

Funder

AO Foundation

National Institutes of Health

Anna-NOREF Foundation

Dutch Arthritis Foundation

Publisher

Wiley

Subject

Biomedical Engineering,Biomaterials,Medicine (miscellaneous)

Reference48 articles.

1. Recombinant human bone morphogenetic protein-2: A randomized trial in open tibial fractures treated with reamed nail fixation;Aro;The Journal of Bone and Joint Surgery. American Volume,2011

2. Properties of chitosan-collagen sponges and osteogenic differentiation of rat-bone-marrow stromal cells;Arpornmaeklong;International Journal of Oral and Maxillofacial Surgery,2008

3. A comprehensive review of the safety profile of bone morphogenetic protein in spine surgery;Benglis;Neurosurgery,2008

4. The kinetic and biological activity of different loaded rhBMP-2 calcium phosphate cement implants in rats;Bodde;Journal of Biomedical Materials Research. Part A,2008

5. Effects of protein dose and delivery system on BMP-mediated bone regeneration;Boerckel;Biomaterials,2011

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