Randomized, placebo‐controlled, phase 3 study of perifosine combined with bortezomib and dexamethasone in patients with relapsed, refractory multiple myeloma previously treated with bortezomib

Author:

Richardson Paul G.1ORCID,Nagler Arnon2,Ben‐Yehuda Dina3,Badros Ashraf4,Hari Parameswaran N.5,Hajek Roman6ORCID,Spicka Ivan7,Kaya Hakan8,LeBlanc Richard9,Yoon Sung‐Soo10,Kim Kihyun11,Martinez‐Lopez Joaquin12ORCID,Mittelman Moshe13,Shpilberg Ofer14,Blake Paul15,Hideshima Teru1,Colson Kathleen1,Laubach Jacob P.1ORCID,Ghobrial Irene M.1,Leiba Merav16,Gatt Moshe E.3ORCID,Sportelli Peter17,Chen Michael18,Anderson Kenneth C.1

Affiliation:

1. Jerome Lipper Center for Multiple Myeloma Research Dana‐Farber Cancer Institute Boston Massachusetts USA

2. Chaim Sheba Medical Center Tel Hashomer Israel

3. Hadassah University Hospital Jerusalem Israel

4. Greenebaum Comprehensive Cancer Center University of Maryland Baltimore Maryland USA

5. Department of Hematology/Oncology Medical College of Wisconsin Milwaukee Wisconsin USA

6. Department of Hematooncology University Hospital, Ostrava, and Faculty of Medicine University of Ostrava Ostrava Czech Republic

7. First Department of Medicine, Department of Hematology First Faculty of Medicine Charles University and General Hospital in Prague Prague Czech Republic

8. Cancer Care Northwest Spokane Washington USA

9. CIUSSS de l'est de l’île de Montréal University of Montreal Montreal Canada

10. Department of Internal Medicine Seoul National University College of Medicine Seoul South Korea

11. Sungkyunkwan University School of Medicine Samsung Medical Center Seoul South Korea

12. Hospital Universitario 12 de Octubre CNIO Complutense University Madrid Spain

13. Tel Aviv Sourasky Medical Center Tel Aviv Israel

14. Institute of Hematology Assuta Medical Centers Tel Aviv and Ariel University Ariel Israel

15. Aeterna Zentaris Frankfurt Germany

16. Assuta Ashdod University Hospital Faculty of Health Sciences Ben‐Gurion University of the Negev Beer‐Sheba Israel

17. Keryx Biopharmaceuticals Inc. New York New York USA

18. TCM Groups Inc. Berkeley Heights New Jersey USA

Funder

RJ Corman Multiple Myeloma Research Fund

Aeterna Zentaris GmbH

AOI Pharmaceuticals, Inc., a subsidiary of Keryx Biopharmaceuticals, Inc.

Publisher

Wiley

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