A computational model for hepatotoxicity by coupling drug transport and acetaminophen metabolism equations
Author:
Affiliation:
1. ENSEEIHTNational Polytechnic Institute of Toulouse Toulouse France
2. Department of Engineering ScienceThe University of Auckland Auckland New Zealand
3. Auckland Bioengineering InstituteThe University of Auckland Auckland New Zealand
Funder
Science for Technological Innovation
Publisher
Wiley
Subject
Applied Mathematics,Computational Theory and Mathematics,Molecular Biology,Modelling and Simulation,Biomedical Engineering,Software
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/cnm.3234
Reference14 articles.
1. Mechanisms of Acetaminophen-Induced Liver Necrosis
2. Adaptation to acetaminophen exposure elicits major changes in expression and distribution of the hepatic proteome
3. ACETAMINOPHEN-INDUCED HEPATOTOXICITY
4. Metabolic zonation of the liver: Regulation and implications for liver function
5. Metabolic zonation of the liver: The oxygen gradient revisited
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