Serenoa repens (Permixon®) inhibits the 5α‐reductase activity of human prostate cancer cell lines without interfering with PSA expression

Author:

Habib Fouad K.1,Ross Margaret1,K.H. Ho Clement1,Lyons Valerie2,Chapman Karen2

Affiliation:

1. Prostate Research Group, University of Edinburgh, School of Molecular and Clinical Medicine, Western General Hospital, Edinburgh, UK

2. Endocrinology Unit, Molecular Medicine Centre, University of Edinburgh, School of Molecular and Clinical Medicine, Western General Hospital, Edinburgh, UK

Funder

Pierre Fabre Medicament

Publisher

Wiley

Subject

Cancer Research,Oncology

Reference22 articles.

1. Molecular effects of the herbal compound PC‐SPES: identification of activity pathways in prostate carcinoma;Bonham M;Cancer Res,2002

2. Serenoa repens (Permixon�): A 5?-reductase types I and II inhibitor?new evidence in a coculture model of BPH

3. Serenoa repens (Permixon®)

4. Effects of the lipidosterolic extract ofSerenoa repens (Permixon®) on human prostatic cell lines

5. Down‐regulation of prostate‐specific antigen expression by finasteride through inhibition of complex formation between androgen receptor and steroid receptor‐binding consensus in the promoter of the PSA gene in LNCaP cells;Wang LG;Cancer Res,1997

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