Local effects of human PCSK9 on the atherosclerotic lesion-Reference-Cited by-同舟云学术

Local effects of human PCSK9 on the atherosclerotic lesion

Published:2015-11-13 Issue:1 Volume:238 Page:52-62
ISSN:0022-3417
Container-title:The Journal of Pathology
language:en
Short-container-title:J. Pathol.

Author:

Giunzioni Ilaria¹,Tavori Hagai¹,Covarrubias Roman²,Major Amy S²,Ding Lei³,Zhang Youmin³,DeVay Rachel M⁴,Hong Liang⁴,Fan Daping⁵,Predazzi Irene M¹,Rashid Shirya⁶,Linton MacRae F³⁷,Fazio Sergio¹

Affiliation:

1. Knight Cardiovascular Institute, Center for Preventive Cardiology; Oregon Health and Science University; Portland OR USA

2. Department of Pathology, Microbiology and Immunology; Vanderbilt University Medical Center; Nashville TN USA

3. Division of Cardiovascular Medicine, Atherosclerosis Research Unit, Department of Medicine; Vanderbilt University Medical Center; Nashville TN USA

4. Rinat-Pfizer Inc.; South San Francisco CA USA

5. University of South Carolina School of Medicine; Columbia SC USA

6. Department of Pharmacology; Dalhousie University, Halifax, Nova Scotia, and Saint John; New Brunswick Canada

7. Department of Pharmacology; Vanderbilt University Medical Center; Nashville TN USA

Funder

National Heart, Lung, and Blood Institute

Publisher

Wiley

Subject

Pathology and Forensic Medicine

Link

http://onlinelibrary.wiley.com/wol1/doi/10.1002/path.4630/fullpdf

Reference51 articles.

1. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia;Abifadel;Nat Genet,2003

2. NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol;Benjannet;J Biol Chem,2004

3. Wild-type PCSK9 inhibits LDL clearance but does not affect apoB-containing lipoprotein production in mouse and cultured cells;Lalanne;J Lipid Res,2005

4. Proprotein convertase subtilisin/kexin type 9 (PCSK9): hepatocyte-specific low-density lipoprotein receptor degradation and critical role in mouse liver regeneration;Zaid;Hepatology,2008

5. Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route;Poirier;J Biol Chem,2009

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