HPLC enantioresolution of (R,S)-baclofen using three newly synthesized dichloro-s-triazine reagents having amines and five others having amino acids as chiral auxiliaries

Author:

Bhushan Ravi1,Dixit Shuchi1

Affiliation:

1. Department of Chemistry; Indian Institute of Technology Roorkee; Roorkee; 247667; India

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Reference26 articles.

1. Baclofen and potential therapeutic use: studies of neuronal survival;Alessandro;European Journal of Pharmacology,2006

2. Marfey's reagent for chiral amino acid analysis: a review;Bhushan;Amino Acids,2004

3. Application of cyanuric chloride based six new chiral derivatizing reagents having amino acids and amino acid amides as chiral auxiliaries for enantioresolution of proteinogenic amino acids by reversed-phase high-performance liquid chromatography;Bhushan;Amino Acids,2010a

4. Enantioresolution of five β-blockers by reversed-phase high-performance liquid chromatography using fifteen chiral derivatizing reagents having amino acids or their amides as chiral auxiliaries on a cyanuric chloride platform;Bhushan;Biomedical Chromatography,2010b

5. Microwave-assisted synthesis and reversed-phase high-performance liquid chromatographic separation of diastereomers of (R,S)-baclofen using ten chiral derivatizing reagents designed from trichloro-s-triazine;Bhushan;Journal of Chromatography A,2010c

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