Whole-exome sequencing and targeted gene sequencing provide insights into the role ofPALB2as a male breast cancer susceptibility gene

Author:

Silvestri Valentina1,Zelli Veronica1,Valentini Virginia1,Rizzolo Piera1,Navazio Anna Sara1,Coppa Anna2,Agata Simona3,Oliani Cristina4,Barana Daniela4,Castrignanò Tiziana5,Viel Alessandra6,Russo Antonio7,Tibiletti Maria Grazia8,Zanna Ines9,Masala Giovanna9,Cortesi Laura10,Manoukian Siranoush11,Azzollini Jacopo11,Peissel Bernard11,Bonanni Bernardo12,Peterlongo Paolo13,Radice Paolo14,Palli Domenico9,Giannini Giuseppe1,Chillemi Giovanni5,Montagna Marco3,Ottini Laura1

Affiliation:

1. Department of Molecular Medicine; Sapienza University of Rome; Rome Italy

2. Department of Experimental Medicine; Sapienza University of Rome; Rome Italy

3. Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV; Padua Italy

4. Oncology Unit, Local Health and Social Care Unit ULSS5 Ovest Vicentino; Montecchio Maggiore Italy

5. Supercomputing Applications and Innovation Department; Interuniversity Consortium for Super Computing CINECA; Rome Italy

6. Unit of Functional Onco-Genomics and Genetics, Aviano Oncology Reference Center CRO, National Cancer Institute; Aviano Italy

7. Section of Medical Oncology, Department of Surgical and Oncological Sciences; University of Palermo; Palermo Italy

8. Unit of Pathology, Circolo Hospital; Varese Italy

9. Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute ISPO; Florence Italy

10. Department of Oncology and Haematology; University of Modena and Reggio Emilia; Modena Italy

11. Unit of Medical Genetics, Department of Preventive and Predictive Medicine, National Cancer Institute INT; Milan Italy

12. Division of Cancer Prevention and Genetics, European Institute of Oncology IEO; Milan Italy

13. Italian Foundation for Cancer Research (FIRC) Institute of Molecular Oncology INT; Milan Italy

14. Unit of Molecular Bases of Genetic Risk and Genetic Testing, Department of Preventive and Predictive Medicine; National Cancer Institute INT; Milan Italy

Funder

Italian Association for Cancer Research

Tuscan Cancer Institute

Umberto Veronesi Foundation

National Cancer Institute

Publisher

Wiley

Subject

Cancer Research,Oncology

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