Lung Delivery of Indacaterol and Mometasone Furoate Following Inhalation of QMF149 in Healthy Volunteers

Author:

Vaidya Soniya S.1,Khindri Sanjeev2,Maahs Suzanne3,Machineni Surendra4,Hara Hisanori5,Juan Axel6,Kaiser Günther7

Affiliation:

1. Drug Metabolism and Pharmacokinetics; Clinical Pharmacokinetics/Pharmacodynamics; Novartis Institutes for BioMedical Research; Cambridge MA USA

2. Translational Medicine; Novartis Institutes for BioMedical Research; Horsham West Sussex UK

3. Translational Medicine; Novartis Institutes for BioMedical Research; East Hanover NJ USA

4. Integrated Information and Sciences; Novartis Healthcare Pvt Ltd; Hyderabad India

5. Drug Metabolism and Pharmacokinetics; Advanced BA & Automation; Novartis Institutes for BioMedical Research; Basel Switzerland

6. Seaview Research; Inc; Miami FL USA

7. Drug Metabolism and Pharmacokinetics; Clinical Pharmacokinetics/Pharmacodynamics; Novartis Institutes for BioMedical Research; Basel Switzerland

Publisher

Wiley

Subject

Pharmacology (medical),Pharmaceutical Science

Reference26 articles.

1. Global Initiative for Asthma (GINA) 2015 http://www.ginasthma.org

2. Global Initiative for Chronic Obstructive Lung Disease (GOLD) Global strategy for the diagnosis, management and prevention of chronic obstructive pulmonary disease 2015 http://www.goldcopd.com

3. Delivery characteristics of a low-resistance dry-powder inhaler used to deliver the long-acting muscarinic antagonist glycopyrronium;Colthorpe;J Drug Assessment,2013

4. Delivery characteristics and patients’ handling of two single-dose dry-powder inhalers used in COPD;Chapman;Int J Chron Obstr Pulmon Dis,2011

5. Indacaterol provides 24-hour bronchodilation in COPD: a placebo-controlled blinded comparison with tiotropium;Vogelmeier;Respir Res,2010

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