Periostin‐ and podoplanin‐positive cancer‐associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma

Author:

Neuzillet Cindy12ORCID,Nicolle Rémy3ORCID,Raffenne Jérôme4,Tijeras‐Raballand Annemilaï5,Brunel Alexia4ORCID,Astorgues‐Xerri Lucile5,Vacher Sophie6ORCID,Arbateraz Floriane7ORCID,Fanjul Marjorie4,Hilmi Marc1,Samain Rémi4,Klein Christophe7ORCID,Perraud Aurélie89,Rebours Vinciane310ORCID,Mathonnet Muriel89,Bièche Ivan6,Kocher Hemant11ORCID,Cros Jérôme312ORCID,Bousquet Corinne4ORCID

Affiliation:

1. Department of Medical Oncology, Institut Curie Université Versailles Saint‐Quentin, Paris Saclay Saint‐Cloud France

2. UMR144, Institut Curie Paris France

3. INSERM U1149, Centre de Recherche sur l'Inflammation Paris France

4. INSERM UMR‐1037, Cancer Research Center of Toulouse (CRCT), Team ‘labellisée Ligue Contre le Cancer’ University of Toulouse Toulouse France

5. OncoMEGA Lamorlaye France

6. Department of Genetics Institut Curie, PSL Research University Paris France

7. Centre d'Histologie Imagerie et Cytométrie (CHIC), U1138 Centre de Recherche des Cordeliers (CRC) Paris France

8. Department of Digestive Surgery University Hospital of Limoges Limoges France

9. INSERM UMLR‐1308 University of Limoges Limoges France

10. Department of Pancreatology Beaujon Hospital (APHP) Clichy‐La‐Garenne France

11. Centre for Tumour Biology, Barts Cancer Institute ‐ a CR‐UK Centre of Excellence Queen Mary University of London London UK

12. Department of Pathology, Beaujon Hospital (APHP) Université de Paris Paris France

Funder

Fondation pour la Recherche Médicale

Société Nationale Française de Gastro-Entérologie

Cancer Research UK

CNIB

Publisher

Wiley

Subject

Pathology and Forensic Medicine

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