Cryptotanshinone Inhibits STAT3 Signaling to Alleviate Cardiac Fibrosis in Type 1-like Diabetic Rats

Author:

Lo Shih-Hsiang12,Hsu Chao-Tien3,Niu Ho-Shan2,Niu Chiang-Shan2,Cheng Juei-Tang456ORCID,Chen Zhih-Cherng457

Affiliation:

1. Division of Cardiology, Department of Internal Medicine; Zhongxing Branch of Taipei City Hospital; Taipei City 10341 Taiwan

2. Department of Nursing; Tzu Chi University of Science and Technology; Hualien City 97041 Taiwan

3. Department of Pathology, E-DA Hospital; I-Shou University; Yanchao Kaohsiung City 82401 Taiwan

4. Department of Cardiology; Chi-Mei Medical Center; Yong Kang Tainan City 71003 Taiwan

5. Department of Medical Research; Chi-Mei Medical Center; Yong Kang Tainan City 71003 Taiwan

6. Institute of Medical Sciences; Chang Jung Christian University; Guiren Tainan City 71101 Taiwan

7. Department of Pharmacy; Chia Nan University of Pharmacy & Science; Jean-Tae City Tainan County 71701 Taiwan

Funder

Department of Health

Publisher

Wiley

Subject

Pharmacology

Reference38 articles.

1. The expression of STAT3, BCL-XL and MMP-2 proteins in colon adenocarcinomas and their relationship with prognostic factors;Artas;Turk patoloji dergisi,2014

2. Diabetic cardiomyopathy;Bell;Diabetes Care,2003

3. Generating double knockout mice to model genetic intervention for diabetic cardiomyopathy in humans;Chavali;Methods Mol Biol,2014

4. Characterization of the mechanisms of the increase in PPARdelta expression induced by digoxin in the heart using the H9c2 cell line;Chen;Br J Pharmacol,2011

5. Novel mechanism for plasma glucose-lowering action of metformin in streptozotocin-induced diabetic rats;Cheng;Diabetes,2006

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