Typical antimicrobials induce mast cell degranulation and anaphylactoid reactions via MRGPRX2 and its murine homologue MRGPRB2

Author:

Zhang Tao1,Che Delu1,Liu Rui1,Han Shengli1,Wang Nan12,Zhan Yingzhuan12,Pundir Priyanka2,Cao Jiao1,Lv Yanni1,Yang Liu1,Wang Jue1,Ding Meiwen1,Dong Xinzhong2,He Langchong1ORCID

Affiliation:

1. School of Pharmacy; Xi'an Jiaotong University; Xi'an China

2. The Solomon H. Snyder Department of Neuroscience, Johns Hopkins University; School of Medicine; Baltimore Maryland USA

Funder

National Natural Science Foundation of China

Publisher

Wiley

Subject

Immunology,Immunology and Allergy

Reference27 articles.

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2. Penicillin skin testing in hospitalized patients with β-lactam allergies: effect on antibiotic selection and cost;King;Ann. Allergy Asthma Immunol.,2016

3. Basophil reactivity as biomarker in immediate drug hypersensitivity reactions-potential and limitations;Steiner;Front. Pharmacol.,2016

4. Effect of ACTH and cortisone upon an anaphylactoid reaction;Selye;Can. Med .Assoc. J.,1949

5. A revised nomenclature for allergy. An EAACI position statement from the EAACI nomenclature task force;Johansson;Allergy,2001

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